Article
KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.
Immunogenetics - 1 Nov 2014
Nemat-Gorgani Neda, Edinur Hisham A, Hollenbach Jill A, Traherne James A, Dunn Paul P J, Chambers Geoffrey K, Parham Peter, Norman Paul J
Abstract excerpt
HLA class I molecules and killer cell immunoglobulin-like receptors (KIR) form a diverse system of ligands and receptors that individualize human immune systems in ways that improve the survival of individuals and populations. Human settlement of Oceania by island-hopping East and Southeast Asian migrants started ~3,500 years ago. Subsequently, New Zealand was reached ~750 years ago by ancestral Māori. To examine...
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