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Article

Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.

Oncology reports - 1 Apr 2007

Vairaktaris Eleftherios, Yapijakis Christos, Yiannopoulos Athanasios, Vassiliou Stavros, Serefoglou Zoe, Vylliotis Antonis, Nkenke Emeka, Derka Spyridoula, Critselis Elena, Avgoustidis Dimitrios, Neukam Friedrich W, Patsouris Efstratios

Abstract excerpt

The present study was performed in order to investigate the possible association of the -418 G/C polymorphism in the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene, which affects its expression, with the risk of developing oral cancer. PCR-based restriction analysis was performed in DNA samples from 158 patients with oral squamous cell carcinoma (OSCC) and 168 healthy controls of equivalent sex, age and...

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PMID: 17342343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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