Article
Polymorphisms in MMP-2 and TIMP-2 in Turkish patients with prostate cancer.
Turkish journal of medical sciences - 1 Jan 2014
Yaykaşli Kürşat Oğuz, Kayikçi Muhammet Ali, Yamak Nesibe, Soğuktaş Hatice, Düzenli Selma, Arslan Ali Osman, Metın Ahmet, Kaya Ertuğrul, Hatıpoğlu Ömer Faruk
Abstract excerpt
AIM: Prostate cancer is the most commonly diagnosed malignancy and the second most common cause of cancer deaths in the Western male population. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) modulate the remodeling of the extracellular matrix (ECM). The imbalance between MMPs and TIMPs may lead to an emergence of pathological processes such as cancer. In this study, the association...
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