Association of TIMP-2 Rs8179090 Genotypes With Lung Cancer Risk in Taiwan.

doi:10.21873/anticanres.15354

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Article

Association of TIMP-2 Rs8179090 Genotypes With Lung Cancer Risk in Taiwan.

Anticancer research - 1 Nov 2021

Liao Wei-Chih, Huang Chien-Wen, Hsia Te-Chun, Shen Yi-Cheng, Chang Wen-Shin, Tsai Chia-Wen, Wang Yun-Chi, Yin Mei-Chin, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: The tissue inhibitor of metalloproteinase-2 (TIMP-2) is a critical inhibitor of matrix metalloproteinases (MMPs). Along with MMPs, TIMP-2 regulates the breakdown and remodeling of the extracellular matrix (ECM) and basement membranes. This study investigated the role of genotypes of the TIMP-2 -418G/C (rs8179090) single nucleotide polymorphism on lung risk. MATERIALS AND METHODS: A total of 358...

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PMID: 34732411
DOI: 10.21873/anticanres.15354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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