Article
Periderm prevents pathological epithelial adhesions during embryogenesis.
The Journal of clinical investigation - 1 Sept 2014
Richardson Rebecca J, Hammond Nigel L, Coulombe Pierre A, Saloranta Carola, Nousiainen Heidi O, Salonen Riitta, Berry Andrew, Hanley Neil, Headon Denis, Karikoski Riitta, Dixon Michael J
Abstract excerpt
Appropriate development of stratified, squamous, keratinizing epithelia, such as the epidermis and oral epithelia, generates an outer protective permeability barrier that prevents water loss, entry of toxins, and microbial invasion. During embryogenesis, the immature ectoderm initially consists of a single layer of undifferentiated, cuboidal epithelial cells that stratifies to produce an outer layer of flattened...
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