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Article

Wound healing and inflammation: embryos reveal the way to perfect repair

15 Apr 2004

Abstract excerpt

Tissue repair in embryos is rapid, efficient and perfect and does not leave a scar, an ability that is lost as development proceeds. Whereas adult wound keratinocytes crawl forwards over the exposed substratum to close the gap, a wound in the embryonic epidermis is closed by contraction of a rapidly assembled actin purse string. Blocking assembly of this cable in chick and mouse embryos, by drugs or by...

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Identifiers

PMID: 15293805
DOI: 10.1098/rstb.2004.1466

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