Article
Direct sequencing and amplification refractory mutation system for epidermal growth factor receptor mutations in patients with non-small cell lung cancer.
Oncology reports - 1 Nov 2013
Chu Huili, Zhong Chen, Xue Guoliang, Liang Xiuju, Wang Jun, Liu Yingxin, Zhao Shiwei, Zhou Qian, Bi Jingwang
Abstract excerpt
Treatment with epidermal growth factor receptor (EGFR) tyrosine inhibitors (EGFR-TKIs) provides encouraging outcomes for advanced non-small cell lung cancer (NSCLC) patients with EGFR mutations. Pleural effusion is a common complication of NSCLC. We compared direct DNA sequencing and ADx Amplification Refractory Mutation System (ADx-ARMS) to detect EGFR mutations in malignant pleural effusion samples. We obtained...
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