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Article

Comprehensive analysis of NGS and ARMS-PCR for detecting EGFR mutations based on 4467 cases of NSCLC patients.

Journal of cancer research and clinical oncology - 1 Feb 2022

He Changlong, Wei Chengcheng, Wen Jun, Chen Shi, Chen Ling, Wu Yue, Shen Yifan, Bai Huili, Zhang Yangli, Chen Xueping, Li Xiaosong

Abstract excerpt

BACKGROUND: By comparing the detection rate and type of targeted gene mutations in non-small cell lung cancer (NSCLC) between amplification refractory mutation system PCR (ARMS-PCR) and next-generation sequencing (NGS), the characteristics and application advantages of non-small cell lung cancer detection are explained, providing a basis for clinicians to effectively select the corresponding detection methods....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34693477
DOI: 10.1007/s00432-021-03818-w
PMCID: PMC8800890

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