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Article

Comparison of ARMS and direct sequencing for detection of EGFR mutation and prediction of EGFR-TKI efficacy between surgery and biopsy tumor tissues in NSCLC patients.

Medical oncology (Northwood, London, England) - 1 May 2014

Shaozhang Zhou, Ming Zhou, Haiyan Peng, Aiping Zeng, Qitao Yu, Xiangqun Song

Abstract excerpt

The relationship between epidermal growth factor receptor (EGFR) mutation status and EGFR-tyrosine kinase inhibitors (TKI) efficacy in non-small cell lung cancer (NSCLC) patients has been well established. However, there is no available standard to define the optimal testing method and specimen type required for the detection of EGFR mutations. In this study, we compare results of ADx-amplification refractory...

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Identifiers

PMID: 24748405
DOI: 10.1007/s12032-014-0926-3

Genes

EGFR

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Comparison of ARMS and direct sequencing for detection of EGFR mutation and prediction of EGFR-TKI efficacy between surgery and biopsy tumor tissues in NSCLC patients.PMID 24748405Read ↗

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