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Article

Porcine NOD1 polymorphisms with impaired ligand recognition and their distribution in pig populations.

Molecular immunology - 1 Feb 2015

Shinkai Hiroki, Matsumoto Toshimi, Toki Daisuke, Okumura Naohiko, Terada Kei, Uenishi Hirohide

Abstract excerpt

Nucleotide-binding oligomerization domain 1 (NOD1) is a cytosolic pattern recognition receptor that recognizes γ-d-glutamyl-meso-diaminopimelic acid (iE-DAP), a component of bacterial peptidoglycan. NOD1 is thought to be involved in the immune homeostasis mediated by intestinal microbiota as well as the host defense against infection. In this study, we identified 12 synonymous and nine nonsynonymous single...

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Identifiers

PMID: 25128158
DOI: 10.1016/j.molimm.2014.07.020

Genes

NOD1
DAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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