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Article

Polymorphisms of the immune-modulating receptor dectin-1 in pigs: their functional influence and distribution in pig populations.

Immunogenetics - 1 Apr 2016

Shinkai Hiroki, Toki Daisuke, Okumura Naohiko, Takenouchi Takato, Kitani Hiroshi, Uenishi Hirohide

Abstract excerpt

Dectin-1, a C-type lectin receptor that recognizes fungal β-glucans, is involved in antifungal immunity and the regulation of intestinal immune homeostasis. Dectin-1 is involved in both synthesis and maturation of interleukin-1β, a key pro-inflammatory cytokine in immunity. Here, we assessed the genetic diversity in the gene encoding dectin-1 (CLEC7A) within various pig populations and examined the influence of...

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Identifiers

PMID: 26762386
DOI: 10.1007/s00251-016-0900-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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