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Article

NOD2 Genotypes Affect the Symptoms and Mortality in the Porcine Circovirus 2-Spreading Pig Population.

Genes - 16 Sept 2021

Suzuki Kasumi, Shinkai Hiroki, Yoshioka Gou, Matsumoto Toshimi, Tanaka Junji, Hayashi Noboru, Kitazawa Haruki, Uenishi Hirohide

Abstract excerpt

The nucleotide oligomerization domain (NOD)-like receptor 2 (NOD2) is an intracellular pattern recognition receptor that detects components of peptidoglycans from bacterial cell walls. NOD2 regulates bowel microorganisms, provides resistance against infections such as diarrhea, and reduces the risk of inflammatory bowel diseases in humans and mice. We previously demonstrated that a specific porcine NOD2...

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Identifiers

PMID: 34573406
DOI: 10.3390/genes12091424
PMCID: PMC8469532

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