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Article

Association of DNA methyltransferases 3A and 3B polymorphisms, and plasma folate levels with the risk of urothelial carcinoma.

PloS one - 1 Jan 2014

Chung Chi-Jung, Chang Chao-Hsiang, Liu Chiu-Shong, Huang Chi-Ping, Chang Yi-Huei, Chien Ssu-Ning, Tsai Ping-Huan, Hsieh Hui-An

Abstract excerpt

BACKGROUND: Interindividual genetic variations of human DNA methyltransferases (DNMTs), which involve the methyl donor from the folate-related one-carbon metabolism pathway, are hypothesized as a risk factor for urothelial carcinoma (UC). Therefore, we evaluated the role of gene-environment interaction in UC carcinogenesis. METHODS: A hospital-based case-control study was conducted by recruiting 192 patients with...

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Identifiers

PMID: 25126948
DOI: 10.1371/journal.pone.0104968
PMCID: PMC4134234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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