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Article

XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma.

Toxicology and applied pharmacology - 15 Sept 2014

Chiang Chien-I, Huang Ya-Li, Chen Wei-Jen, Shiue Horng-Sheng, Huang Chao-Yuan, Pu Yeong-Shiau, Lin Ying-Chin, Hsueh Yu-Mei

Abstract excerpt

The association between DNA repair gene polymorphisms and bladder cancer has been widely studied. However, few studies have examined the correlation between urothelial carcinoma (UC) and arsenic or its metabolites. The aim of this study was to examine the association between polymorphisms of the DNA repair genes, XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln, with urinary arsenic profiles...

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Share to Arsenic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spectrophotometry, Atomic

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Share to X-ray Repair Cross Complementing Protein 1

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 25018058
DOI: 10.1016/j.taap.2014.06.027

Genes

XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma.PMID 25018058Read ↗

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XRCC1 genetic polymorphisms and bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

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