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Article

Screening of the GPX3 gene identifies the "T" allele of the SNP -861A/T as a risk for ischemic stroke in young Asian Indians.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Sept 2014

Akhter Mohammad S, Biswas Arijit, Rashid Hina, Devi Luxmi, Behari Madhuri, Saxena Renu

Abstract excerpt

BACKGROUND: Deficiency of plasma glutathione peroxidase (GPx-3) has been associated with platelet-dependent thrombosis. Single-nucleotide polymorphisms (SNPs) in the promoter region of GPX3 gene have been found associated with the risk for ischemic stroke in Caucasian populations. The aim of our present study was to evaluate the impact of genetic variations in the GPX3 gene and plasma GPx-3 antigen levels on...

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Source

Identifiers

PMID: 25126700
DOI: 10.1016/j.jstrokecerebrovasdis.2014.03.010

Genes

GPX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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