Article
Association of tag SNPs of GPx-3 with essential hypertension in rural Han Chinese in Fuxin, Liaoning, China.
Chinese medical journal - 1 Jul 2011
Hao Ying, Wu Bao-gang, Shi Jin, Chen Yan-li, Sun Zhao-qing, Zheng Li-qiang, Zhang Xin-gang, Geng Ning, Li Tie-jun, Li Hong, Sun Ying-xian
Abstract excerpt
BACKGROUND: Genetic mechanisms contribute to blood pressure regulation. This study investigated whether glutathione peroxidase (GPx-3) tag single nucleotide polymorphisms (SNPs) are associated with hypertension in the rural areas of Fuxin county, Liaoning province, China. METHODS: Indigenous Fuxin Han people participated, 523 unrelated hypertensives and 547 controls were recruited. All tag SNPs of GPx-3 gene were...
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