Article
Platelet glycoprotein gene Ia C807T, HPA-3, and Ibα VNTR polymorphisms are associated with increased ischemic stroke risk: Evidence from a comprehensive meta-analysis.
International journal of stroke : official journal of the International Stroke Society - 1 Jan 2017
Liu Hua, Wang Yi, Zheng Jian, Li Guangming, Chen Tao, Lei Jianguo, Mao Yiting, Wang Jun, Liu Wei, Zhao Ge, Tacey Mark, Yan Bernard
Abstract excerpt
Background/aims Platelet glycoproteins play a crucial role in the initial stage of thrombus formation and may contribute to the pathophysiology of atherosclerosis. Polymorphisms in glycoprotein genes alter the function of the protein, possibly leading to increased risk of ischemic stroke. However, previous genetic association studies that examined the relationship between glycoprotein genes polymorphisms and...
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