Article
Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2008
Pera Joanna, Slowik Agnieszka, Dziedzic Tomasz, Pulyk Roman, Wloch Dorota, Szczudlik Andrzej
Abstract excerpt
BACKGROUND: Oxidative stress plays an important role in vascular pathology and contributes to the pathophysiology of primary intracerebral hemorrhage (PICH). Glutathione peroxidase 1 (GPX1) is a key enzyme of the antioxidant system. Here, we investigated whether a functional C593T polymorphism of GPX1 gene is associated with PICH in a Polish population. METHODS: Genotyping was performed in 192 PICH patients and...
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