Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis.

Stroke - 1 Feb 2008

Voetsch Barbara, Jin Richard C, Bierl Charlene, Deus-Silva Leonardo, Camargo Erica C S, Annichino-Bizacchi Joyce M, Handy Diane E, Loscalzo Joseph

Abstract excerpt

BACKGROUND AND PURPOSE: Plasma glutathione peroxidase (GPx-3) is a major antioxidant enzyme in plasma and the extracellular space that scavenges reactive oxygen species produced during normal metabolism or after oxidative insult. A deficiency of this enzyme increases extracellular oxidant stress,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glutathione Peroxidase
Share to Hormones
Share to Intracranial Thrombosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

Share to Stroke

Share to Venous Thrombosis

Source

Identifiers

PMID: 18096833
DOI: 10.1161/STROKEAHA.107.490094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18096833-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis.PMID 18096833Read ↗

Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children.Semantic proximity Read ↗

Screening of the GPX3 gene identifies the "T" allele of the SNP -861A/T as a risk for ischemic stroke in young Asian Indians.Semantic proximity Read ↗

Plasma glutathione peroxidase in pediatric stroke families.Semantic proximity Read ↗

Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage.Semantic proximity Read ↗

Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.Semantic proximity Read ↗

The C718T polymorphism in the 3'-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension.Semantic proximity Read ↗

Polymorphisms of antioxidant enzymes, blood pressure and risk of hypertension.Semantic proximity Read ↗

Glutathione peroxidase 3 gene polymorphisms and the risk of sudden sensorineural hearing loss.Semantic proximity Read ↗

Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue.Semantic proximity Read ↗

A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism.Semantic proximity Read ↗

Association of the protein C promoter CG haplotype and the factor II G20210A mutation is a risk factor for cerebral venous thrombosis.Semantic proximity Read ↗

Promotor polymorphisms of plasminogen activator inhibitor-1 and other thrombophilic genotypes in cerebral venous thrombosis: a case-control study in adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.