Article
Glutathione peroxidase 3 gene polymorphisms and the risk of sudden sensorineural hearing loss.
The Kaohsiung journal of medical sciences - 1 Jul 2017
Chien Chen-Yu, Huang Tzu-Yen, Tai Shu-Yu, Chang Ning-Chia, Wang Hsun-Mo, Wang Ling-Feng, Ho Kuen-Yao
Abstract excerpt
The glutathione peroxidase 3 gene (GPX3) is reported to be a risk factor for arterial ischaemic stroke and cerebral venous thrombosis. GPX3 may be one of the aetiologies of sudden sensorineural hearing loss (SSNHL), which might be attributed to the genetic effect of GPX3 by influence reactive oxygen species (ROS). Unbalanced ROS have been associated with susceptibility to SSNHL. Therefore, we conducted a...
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