Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix.

Pathology, research and practice - 1 Nov 2014

Halle Mari Kyllesø, Krakstad Camilla, Engerud Hilde, Bertelsen Bjørn, Salvesen Helga B

Abstract excerpt

Many emerging tools for comprehensive molecular profiling of malignant lesions demand fresh frozen tissue with a high tumor purity. Often, a tumor epithelial content of at least 80% is recommended. This approach may lead to a systematic bias, and therefore we explore if this introduces a selection of cases with a certain phenotype in cervical cancer. Clinicopathologic data for a population-based cohort of 328...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cervix Uteri

Share to Disease-Free Survival

Share to Neoplasm Staging

Share to Paraffin Embedding

Share to Specimen Handling

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 25123963
DOI: 10.1016/j.prp.2014.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix.PMID 25123963Read ↗

Weakly-Supervised Tumor Purity Prediction From Frozen H&E Stained SlidesSemantic proximity Read ↗

Systematic pan-cancer analysis of tumour puritySemantic proximity Read ↗

Impact of Tumor Purity on Immune Gene Expression and Clustering Analyses across Multiple Cancer Types.Semantic proximity Read ↗

Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancerSemantic proximity Read ↗

Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancerSemantic proximity Read ↗

Deriving tumor purity from cancer next generation sequencing data: applications for quantitative ERBB2 (HER2) copy number analysis and germline inference of BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironmentSemantic proximity Read ↗

Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD)Semantic proximity Read ↗

PUREE: accurate pan-cancer tumor purity estimation from gene expression dataSemantic proximity Read ↗

Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data.Semantic proximity Read ↗

Systematic Assessment of Tumor Purity and Its Clinical ImplicationsSemantic proximity Read ↗

Improved Tumor Purity Metrics in Next-generation Sequencing for Clinical Practice: The Integrated Interpretation of Neoplastic Cellularity and Sequencing Results (IINCaSe) Approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.