Article
Co-expression of delta-catenin and RhoA is significantly associated with a malignant lung cancer phenotype.
International journal of clinical and experimental pathology - 1 Jan 2014
Zhang Di, Zhang Jun-Yi, Dai Shun-Dong, Liu Shu-Li, Liu Yang, Tang Na, Wang En-Hua
Abstract excerpt
Delta-catenin, a member of the p120-catenin subfamily, and the Rho GTPase RhoA both have roles in the regulation of the cytoskeleton. In this study, we found that delta-catenin positive expression and RhoA over-expression is consistently found in non-small cell lung cancer, but not in normal lung tissue, and that their co-expression was significantly associated with histological type, differentiation, pTNM stage,...
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