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Article

Defining the recognition elements of Lewis Y-reactive antibodies.

PloS one - 1 Jan 2014

Saha Somdutta, Pashov Anastas, Siegel Eric R, Murali Ramachandran, Kieber-Emmons Thomas

Abstract excerpt

Antibody response to carbohydrate antigens is often independent of T cells and the process of affinity/specificity improvement is considered strictly dependent on the germinal centers. Antibodies induced during a T cell-independent type 2 (TI-2) response are less variable and less functionally versatile than those induced with T cell help. The antigen specificity consequences of accumulation of somatic mutations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25117628
DOI: 10.1371/journal.pone.0104208
PMCID: PMC4130537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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