Article
Mutations in microRNA binding sites of CEP genes involved in cancer.
Cell biochemistry and biophysics - 1 Dec 2014
Gopalakrishnan Chandrasekhar, Kamaraj Balu, Purohit Rituraj
Abstract excerpt
The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we found that 16 of the CEP genes are a potential target to miRNA that binds to complementary...
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