Article
Computational investigation of pathogenic nsSNPs in CEP63 protein.
Gene - 15 Jul 2012
Kumar Ambuj, Purohit Rituraj
Abstract excerpt
Centrosomes are central regulators of mitosis that are often amplified in cancer cells. Centrosomal protein of 63kDa (CEP63) is a centrosomal protein that has an effective role in mitotic spindle assembly and cell cycle regulation. Genetic alterations in CEP63 coding gene has been widely studied for inducing aneuploidy and solid tumors in humans. The nonsynonymous single nucleotide polymorphisms (nsSNPs) are a...
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