Article
Polymorphism in miRNA target sites of CEP-63 and CEP-152 ring complex influences expression of CEP genes and favors tumorigenesis in glioma.
Future oncology (London, England) - 1 Sept 2021
Mahjabeen Ishrat, Maqsood Yusra, Abbasi Ramsha, Ahmed Malik Waqar, Kayani Mahmood Akhtar
Abstract excerpt
Purpose: The present study was designed to screen the genetic polymorphisms and expression profiling of CEP-152 and CEP-63 genes in brain tumor patients. Methods: The amplification refractory mutation system PCR technique (ARMS-PCR) was used for mutation analysis using 300 blood samples of brain tumor patients and 300 overtly healthy controls. For expression analysis, 150 brain tumor tissue samples along with...
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