Article
miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines.
PloS one - 1 Jan 2012
Zhang Wensheng, Edwards Andrea, Zhu Dongxiao, Flemington Erik K, Deininger Prescott, Zhang Kun
Abstract excerpt
In metazoans, miRNAs regulate gene expression primarily through binding to target sites in the 3' UTRs (untranslated regions) of messenger RNAs (mRNAs). Cis-acting variants within, or close to, a gene are crucial in explaining the variability of gene expression measures. Single nucleotide polymor...
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