Article
Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.
Diabetologia - 1 Nov 2014
Nair Anup K, Muller Yunhua Li, McLean Nellie A, Abdussamad Maryam, Piaggi Paolo, Kobes Sayuko, Weil E Jennifer, Curtis Jeffrey M, Nelson Robert G, Knowler William C, Hanson Robert L, Baier Leslie J
Abstract excerpt
AIM/HYPOTHESIS: A recent genome-wide trans-ancestry meta-analysis identified seven new loci associated with type 2 diabetes. We assessed the replication of the seven lead single nucleotide polymorphisms (SNPs) and evaluated these loci for additional signals in American Indians. METHODS: Seven SNPs were genotyped in 7,710 individuals from a longitudinally studied American Indian population, and associations with...
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