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Article

Genetics of age-related macular degeneration: current concepts, future directions.

Seminars in ophthalmology - 1 May 2011

Deangelis Margaret M, Silveira Alexandra C, Carr Elizabeth A, Kim Ivana K

Abstract excerpt

Age-related macular degeneration (AMD) is a progressive degenerative disease which leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 million individuals in the United States are affected by the advanced form of AMD. The etiological pathway of AMD is not yet fully understood, but there is a clear genetic influence on disease risk. To date, the 1q32 (CFH) and 10q26...

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Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 10
Complement Factor H
High-Temperature Requirement A Serine Peptidase 1
Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macular Degeneration

Serine Endopeptidases

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Identifiers

PMID: 21609220
DOI: 10.3109/08820538.2011.577129
PMCID: PMC4242505

Genes

ARMS2
CFH
HTRA1
PLEKHA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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