Article
Genetic aspects of age-related macular degeneration.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie - 1 Jun 2005
MacDonald Ian M
Abstract excerpt
Age-related macular degeneration (AMD) is a complex phenotype that has multiple causes, including genetic. This paper reviews pertinent single-gene disorders, polymorphisms in the human genome that modify disease severity, and maculopathies that provide insight into the pathogenesis of AMD and the function of the normal macula. The availability of DNA-based analysis for certain genes will likely increase the...
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