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Article

The association of genes involved in the angiogenesis-associated signaling pathway with risk of anterior cruciate ligament rupture.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Dec 2014

Rahim Masouda, Gibbon Andrea, Hobbs Hayden, van der Merwe Willem, Posthumus Michael, Collins Malcolm, September Alison V

Abstract excerpt

Angiogenesis-associated signaling is a fundamental component in the remodeling of the extracellular matrix in response to loading. Genes encoding protein components within this signaling cascade are therefore suitable candidates for investigation into ACL injury susceptibility: namely, vascular endothelial growth factor A isoform (VEGFA), kinase insert-domain receptor (KDR), nerve growth factor (NGF), and hypoxia...

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Source

Identifiers

PMID: 25111568
DOI: 10.1002/jor.22705

Genes

VEGFA
KDR
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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