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Article

Investigation of angiogenesis genes with anterior cruciate ligament rupture risk in a South African population.

Journal of sports sciences - 1 Mar 2018

Rahim Masouda, Hobbs Hayden, van der Merwe Willem, Posthumus Michael, Collins Malcolm, September Alison V

Abstract excerpt

The angiogenesis-signalling pathway is a physiological response after mechanical loading to promote matrix remodelling and thereby maintain tissue homeostasis. Studies have shown increased expression of angiogenic molecules in response to loading and in ruptured ligaments. Recently, polymorphisms within the vascular endothelial growth factor A (VEGFA) and kinase insert-domain receptor (KDR) genes were associated...

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Source

Identifiers

PMID: 28502223
DOI: 10.1080/02640414.2017.1322710

Genes

KDR
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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