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Article

Genes encoding proteoglycans are associated with the risk of anterior cruciate ligament ruptures.

British journal of sports medicine - 1 Dec 2014

Mannion Sasha, Mtintsilana Asanda, Posthumus Michael, van der Merwe Willem, Hobbs Hayden, Collins Malcolm, September Alison V

Abstract excerpt

BACKGROUND: Genetic variants within genes involved in fibrillogenesis have previously been implicated in anterior cruciate ligament (ACL) injury susceptibility. Proteoglycans also have important functions in fibrillogenesis and maintaining the structural integrity of ligaments. Genes encoding proteoglycans are plausible candidates to be investigated for associations with ACL injury susceptibility; polymorphisms...

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Identifiers

PMID: 24552666
DOI: 10.1136/bjsports-2013-093201

Genes

DCN
ACAN
BGN
LUM
FMOD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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