Investigation of multiple populations highlight VEGFA polymorphisms to modulate anterior cruciate ligament injury.

doi:10.1002/jor.25192

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Article

Investigation of multiple populations highlight VEGFA polymorphisms to modulate anterior cruciate ligament injury.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2022

Feldmann Daneil C, Rahim Masouda, Suijkerbuijk Mathijs A M, Laguette Mary-Jessica N, Cieszczyk Paweł, Ficek Krzysztof, Huminska-Lisowska Kinga, Häger Charlotte K, Stattin Evalena, Nilsson Kjell G, Alvarez-Rumero Javier, Eynon Nir, Feller Julian, Tirosh Oren, Posthumus Michael, Chimusa Emile R, Collins Malcolm, September Alison V

Abstract excerpt

Polymorphisms in VEGFA and KDR encoding proteins have been associated with anterior cruciate ligament (ACL) injury risk. We leveraged a collective sample from Sweden, Poland, and Australia to investigate the association of functional polymorphisms in VEGFA and KDR with susceptibility to ACL injury risk. Using a case-control genetic association approach, polymorphisms in VEGFA and KDR were genotyped and haplotypes...

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PMID: 34664319
DOI: 10.1002/jor.25192

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