Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers.

PloS one - 1 Jan 2012

Vermehren Johannes, Lötsch Jörn, Susser Simone, Wicker Sabine, Berger Annemarie, Zeuzem Stefan, Sarrazin Christoph, Doehring Alexandra

Abstract excerpt

BACKGROUND AND AIMS: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant associations were observed for the A alleles of HLA-DPA1 rs3077 and HLA-DPB1 rs9277535, which conferred a decreased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Asian People
Share to DNA, Viral
Share to Hepatitis B
Share to Hepatitis B Surface Antigens
Share to Hepatitis B virus
Share to Heterozygote
Share to HLA-DP alpha-Chains
Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 22448225
DOI: 10.1371/journal.pone.0032605
PMCID: PMC3308944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers.PMID 22448225Read ↗

Association between chronic hepatitis B virus infection and HLA-DP gene polymorphisms in the Turkish population.Semantic proximity Read ↗

Role of HLA-DP polymorphisms on chronicity and disease activity of hepatitis B infection in Southern Chinese.Semantic proximity Read ↗

Protective effects of HLA-DPA1/DPB1 variants against Hepatitis B virus infection in an Indonesian population.Semantic proximity Read ↗

Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.Semantic proximity Read ↗

Genetic polymorphisms of HLA-DP and isolated anti-HBc are important subsets of occult hepatitis B infection in Indonesian blood donors: a case-control study.Semantic proximity Read ↗

A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.Semantic proximity Read ↗

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.Semantic proximity Read ↗

Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.Semantic proximity Read ↗

Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population.Semantic proximity Read ↗

Relationship between HLA-DP gene polymorphisms and clearance of chronic hepatitis B virus infections: case-control study and meta-analysis.Semantic proximity Read ↗

HLA-DP and γ-interferon receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection.Semantic proximity Read ↗

Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.