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Article

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance.

Nature - 9 Apr 2009

Tateishi Keisuke, Okada Yuki, Kallin Eric M, Zhang Yi

Abstract excerpt

Recent studies indicate that the methylation state of histones can be dynamically regulated by histone methyltransferases and demethylases. The H3K9-specific demethylase Jhdm2a (also known as Jmjd1a and Kdm3a) has an important role in nuclear hormone receptor-mediated gene activation and male germ cell development. Through disruption of the Jhdm2a gene in mice, here we demonstrate that Jhdm2a is critically...

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Identifiers

PMID: 19194461
DOI: 10.1038/nature07777
PMCID: PMC4085783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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