Article
Dietary alleviation of maternal obesity and diabetes: increased resistance to diet-induced obesity transcriptional and epigenetic signatures.
PloS one - 1 Jan 2013
Attig Linda, Vigé Alexandre, Gabory Anne, Karimi Moshen, Beauger Aurore, Gross Marie-Sylvie, Athias Anne, Gallou-Kabani Catherine, Gambert Philippe, Ekstrom Tomas J, Jais Jean-Philippe, Junien Claudine
Abstract excerpt
According to the developmental origins of health and diseases (DOHaD), and in line with the findings of many studies, obesity during pregnancy is clearly a threat to the health and well-being of the offspring, later in adulthood. We previously showed that 20% of male and female inbred mice can cope with the obesogenic effects of a high-fat diet (HFD) for 20 weeks after weaning, remaining lean. However the feeding...
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