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Article

Focality, stochasticity and neuroanatomic propagation in ALS pathogenesis.

Experimental neurology - 1 Dec 2014

Ravits John

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) phenotypes such as limb ALS, bulbar ALS, primary lateral sclerosis and primary muscular atrophy are highly heterogeneous and exist on a continuum. These are largely determined by the neuroanatomy of the underlying pathological changes, which can be clinically imputed. Deconstructing these early in disease, before temporal-spatial summation induces complexity, shows that ALS...

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Identifiers

PMID: 25108067
DOI: 10.1016/j.expneurol.2014.07.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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