Article
Restraint of the G2/M transition by the SR/RRM family mRNA shuttling binding protein SNXAHRB1 in Aspergillus nidulans.
Genetics - 1 Oct 2014
James Steven W, Banta Travis, Barra James, Ciraku Lorela, Coile Clifford, Cuda Zach, Day Ryan, Dixit Cheshil, Eastlack Steven, Giang Anh, Goode James, Guice Alexis, Huff Yulon, Humbert Sara, Kelliher Christina, Kobie Julie, Kohlbrenner Emily, Mwambutsa Faustin, Orzechowski Amanda, Shingler Kristin, Spell Casey, Anglin Sarah Lea
Abstract excerpt
Control of the eukaryotic G2/M transition by CDC2/CYCLINB is tightly regulated by protein-protein interactions, protein phosphorylations, and nuclear localization of CDC2/CYCLINB. We previously reported a screen, in Aspergillus nidulans, for extragenic suppressors of nimX2(cdc2) that resulted in the identification of the cold-sensitive snxA1 mutation. We demonstrate here that snxA1 suppresses defects in...
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