Article
Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation.
Nucleic acids research - 1 Sept 2014
Yang Jen-Hao, Chiou Yi-Ying, Fu Shu-Ling, Shih I-Yun, Weng Tsai-Hsuan, Lin Wey-Jinq, Lin Chao-Hsiung
Abstract excerpt
Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA/DNA-binding protein involved in chromatin remodeling, RNA processing and the DNA damage response. In addition, increased hnRNPK expression has been associated with tumor development and progression. A variety of post-translational modifications of hnRNPK have been identified and shown to regulate hnRNPK function, including phosphorylation,...
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