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Article

Arginine Methylation of hnRNPK Inhibits the DDX3-hnRNPK Interaction to Play an Anti-Apoptosis Role in Osteosarcoma Cells.

International journal of molecular sciences - 9 Sept 2021

Chen Chiao-Che, Yang Jen-Hao, Fu Shu-Ling, Lin Wey-Jinq, Lin Chao-Hsiung

Abstract excerpt

Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA/DNA binding protein involved in diverse cell processes; it is also a p53 coregulator that initiates apoptosis under DNA damage conditions. However, the upregulation of hnRNPK is correlated with cancer transformation, progression, and migration, whereas the regulatory role of hnRNPK in cancer malignancy remains unclear. We previously showed that arginine...

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Identifiers

PMID: 34575922
DOI: 10.3390/ijms22189764
PMCID: PMC8469703

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Arginine Methylation of hnRNPK Inhibits the DDX3-hnRNPK Interaction to Play an Anti-Apoptosis Role in Osteosarcoma Cells.PMID 34575922Read ↗

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