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Article

Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage.

Cell death & disease - 8 May 2014

Dashzeveg N, Taira N, Lu Z-G, Kimura J, Yoshida K

Abstract excerpt

The tumor suppressor gene p53 regulates apoptosis in response to DNA damage. Promoter selectivity of p53 depends on mainly its phosphorylation. Particularly, the phosphorylation at serine-46 of p53 is indispensable in promoting pro-apoptotic genes that are, however, poorly determined. In the current study, we identified palmdelphin as a pro-apoptotic gene induced by p53 in a phosphorylated serine-46-specific...

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Identifiers

PMID: 24810057
DOI: 10.1038/cddis.2014.176
PMCID: PMC4047856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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