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Article

A metabolic strategy to enhance long-term survival by Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast.

Aging - 1 Jul 2014

Kim Ji-Yoon, Kim Eun-Jung, Lopez-Maury Luis, Bähler Jürg, Roe Jung-Hye

Abstract excerpt

In the fission yeast Schizosaccharomyces pombe, the stationary phase-specific transcription factor Phx1 contributes to long-term survival, stress tolerance, and meiosis. We identified Phx1-dependent genes through transcriptome analysis, and further analyzed those related with carbohydrate and thiamine metabolism, whose expression decreased in ∆phx1. Consistent with mRNA changes, the level of thiamine...

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Identifiers

PMID: 25102102
DOI: 10.18632/aging.100682
PMCID: PMC4153625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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