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Article

Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance.

Molecular systems biology - 1 Apr 2020

Kamrad Stephan, Grossbach Jan, Rodríguez-López Maria, Mülleder Michael, Townsend StJohn, Cappelletti Valentina, Stojanovski Gorjan, Correia-Melo Clara, Picotti Paola, Beyer Andreas, Ralser Markus, Bähler Jürg

Abstract excerpt

Cells balance glycolysis with respiration to support their metabolic needs in different environmental or physiological contexts. With abundant glucose, many cells prefer to grow by aerobic glycolysis or fermentation. Using 161 natural isolates of fission yeast, we investigated the genetic basis and phenotypic effects of the fermentation-respiration balance. The laboratory and a few other strains depended more on...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32319721
DOI: 10.15252/msb.20199270
PMCID: PMC7175467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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