Article
Human natural killer (NK) cells: requirements for cell proliferation and expansion of phenotypically novel subpopulations.
Immunology and cell biology - 1 Apr 1993
Warren H S, Kinnear B F, Skipsey L J
Abstract excerpt
Previous studies established that the high density (resting) natural killer (NK) cell subset (R-NK) of peripheral blood NK cells is unresponsive to interleukin-2 (IL-2) but can be induced to proliferate when cultured with gamma-irradiated malignant melanoma (MM-170) cells or mitomycin-C-treated activated T cells in the presence of an IL-2-conditioned medium (IL-2-CM). This study has examined additional...
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