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Article

Transcriptional regulation of α1H T-type calcium channel under hypoxia.

American journal of physiology. Cell physiology - 1 Oct 2014

Sellak Hassan, Zhou Chun, Liu Bainan, Chen Hairu, Lincoln Thomas M, Wu Songwei

Abstract excerpt

The low-voltage-activated T-type Ca(2+) channels play an important role in mediating the cellular responses to altered oxygen tension. Among three T-type channel isoforms, α1G, α1H, and α1I, only α1H was found to be upregulated under hypoxia. However, mechanisms underlying such hypoxia-dependent isoform-specific gene regulation remain incompletely understood. We, therefore, studied the hypoxia-dependent...

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Identifiers

PMID: 25099734
DOI: 10.1152/ajpcell.00210.2014
PMCID: PMC4187058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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