Article
Trans-ethnic meta-analysis of white blood cell phenotypes.
Human molecular genetics - 20 Dec 2014
Keller Margaux F, Reiner Alexander P, Okada Yukinori, van Rooij Frank J A, Johnson Andrew D, Chen Ming-Huei, Smith Albert V, Morris Andrew P, Tanaka Toshiko, Ferrucci Luigi, Zonderman Alan B, Lettre Guillaume, Harris Tamara, Garcia Melissa, Bandinelli Stefania, Qayyum Rehan, Yanek Lisa R, Becker Diane M, Becker Lewis C, Kooperberg Charles, Keating Brendan, Reis Jared, Tang Hua, Boerwinkle Eric, Kamatani Yoichiro, Matsuda Koichi, Kamatani Naoyuki, Nakamura Yusuke, Kubo Michiaki, Liu Simin, Dehghan Abbas, Felix Janine F, Hofman Albert, Uitterlinden André G, van Duijn Cornelia M, Franco Oscar H, Longo Dan L, Singleton Andrew B, Psaty Bruce M, Evans Michelle K, Cupples L Adrienne, Rotter Jerome I, O'Donnell Christopher J, Takahashi Atsushi, Wilson James G, Ganesh Santhi K, Nalls Mike A
Abstract excerpt
White blood cell (WBC) count is a common clinical measure used as a predictor of certain aspects of human health, including immunity and infection status. WBC count is also a complex trait that varies among individuals and ancestry groups. Differences in linkage disequilibrium structure and heterogeneity in allelic effects are expected to play a role in the associations observed between populations. Prior...
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