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Article

A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype.

Human heredity - 1 Jan 2014

Kang Guolian, Bi Wenjian, Zhao Yanlong, Zhang Ji-Feng, Yang Jun J, Xu Heng, Loh Mignon L, Hunger Stephen P, Relling Mary V, Pounds Stanley, Cheng Cheng

Abstract excerpt

We propose in this paper a set-valued (SV) system model, which is a generalized form of logistic (LG) and Probit (Probit) regression, to be considered as a method for discovering genetic variants, especially rare genetic variants in next-generation sequencing studies, for a binary phenotype. We propose a new SV system identification method to estimate all underlying key system parameters for the Probit model and...

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PMID: 25096228
DOI: 10.1159/000363660
PMCID: PMC4270367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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