Article
A Robust and Powerful Set-Valued Approach to Rare Variant Association Analyses of Secondary Traits in Case-Control Sequencing Studies.
Genetics - 1 Mar 2017
Kang Guolian, Bi Wenjian, Zhang Hang, Pounds Stanley, Cheng Cheng, Shete Sanjay, Zou Fei, Zhao Yanlong, Zhang Ji-Feng, Yue Weihua
Abstract excerpt
In many case-control designs of genome-wide association (GWAS) or next generation sequencing (NGS) studies, extensive data on secondary traits that may correlate and share the common genetic variants with the primary disease are available. Investigating these secondary traits can provide critical...
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