Article
A power set-based statistical selection procedure to locate susceptible rare variants associated with complex traits with sequencing data.
Bioinformatics (Oxford, England) - 15 Aug 2014
Sun Hokeun, Wang Shuang
Abstract excerpt
MOTIVATION: Existing association methods for rare variants from sequencing data have focused on aggregating variants in a gene or a genetic region because of the fact that analysing individual rare variants is underpowered. However, these existing rare variant detection methods are not able to identify which rare variants in a gene or a genetic region of all variants are associated with the complex diseases or...
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